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New York Yankees vs Detroit Tigers Predictions

June 22 06:10 PM (Start in 12 Hours)
DSN Comerica Park

Yankees vs. Tigers Matchup Overview

The New York Yankees visit Comerica Park to take on the Detroit Tigers on June 22nd, 2026, at 6:10 pm. New York holds a record of 46-29, while Detroit sits at 32-44. For those looking to place bets, check out the current moneyline with the Yankees at -125 and the Tigers at +110. The Edge AI sports betting tool can help you find the best bets for this matchup. Key players to watch include Ben Rice for the Yankees, who boasts a .288 batting average with 21 home runs and a .987 OPS. Riley Greene leads the Tigers with a .287 average and 8 home runs. JosΓ© Caballero is out for the Yankees due to a finger injury, and Trent Grisham is questionable with a knee issue, which could impact New York’s lineup. Recent matchups have seen the Yankees win two out of three against the Tigers, adding some intrigue to this contest.

Matchup Overview

  • Teams: New York Yankees vs Detroit Tigers
  • Date: Monday, June 22, 2026
  • Time: 6:10 PM
  • Venue: Comerica Park

Current Betting Odds

  • Spread: Yankees β€” (β€”) (-1.5 (+134 BetMGM Sportsbook)), Tigers β€” (β€”) (+1.5 (-162 BetMGM Sportsbook))
  • Total (Over/Under): 8.0 (-117/-105) (Over 8.0 (-118 BetMGM Sportsbook), Under 8.0 (-104 BetMGM Sportsbook))
  • Moneyline Odds: Yankees -125 (-124 (BetMGM Sportsbook)), Tigers +110 (+106 (BetMGM Sportsbook))

Edge AI Win Probabilities

After 1,000 simulations, our model gives the Yankees a win probability of 54%, while the Tigers have a win probability of 46%

Historically, the Yankees and Tigers have had a competitive rivalry, with the Yankees holding a slight edge in their all-time record. The Yankees’ power-hitting style often clashes with the Tigers’ more balanced approach, creating intriguing matchups. Home field advantage at Comerica Park can shift dynamics, especially considering its spacious dimensions, which can favor pitchers and affect run production in tight games.

Projected Final Score

Our Edge AI predicts a final score of Yankees 5-3 Tigers with a confidence score of 70%. These projections are based on 1,000 simulations and hundreds of data points, ensuring you have the most accurate predictions to inform your betting strategy.

Point Spread
54%
46%
Confidence Level: 70.2%

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Over/Under
54%
46%
Confidence Level: 60.3%

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Moneyline
54%
46%
Confidence Level: 68.5%

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When the Yankees roll into Detroit, it’s a clash of styles that’s hard to ignore. New York’s power hitters thrive on the road, often taking advantage of Comerica Park’s spacious outfield, while the Tigers have historically leaned on solid pitching to keep games close. Over the years, the moneyline tends to favor the Yankees, especially when they’re facing a Tigers squad that struggles against strong lineups, making this matchup one to watch for value in the betting market.

New York Yankees vs Detroit Tigers Moneyline

The Yankees are favored on the moneyline against the Tigers, reflecting their stronger record and recent performance. However, with key injuries to players like JosΓ© Caballero, the Tigers could capitalize on any weaknesses in New York’s lineup, making this matchup one to watch for bettors considering their options.

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When the Yankees head to Detroit, you’re dealing with a classic contrast. The Yankees’ power-hitting style can often dominate, but Comerica Park’s spacious outfield tends to suppress those big flies, which can make the run line tricky. Historically, the Yankees have had a solid edge in this matchup, but the Tigers can surprise at home with their scrappy play, especially against left-handed pitching. Bettors should keep an eye on how these teams perform in the late innings, as both have shown tendencies to either rally or collapse, impacting those run lines significantly.

New York Yankees vs Detroit Tigers Run Line

The New York Yankees, with a solid away record, could cover the run line against the Detroit Tigers. However, the Tigers have shown they can keep games close, especially at home, which might challenge New York’s ability to pull away. Pitching matchups and offensive output will play crucial roles in determining if the Yankees can stretch their lead enough to beat the spread.

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New York Yankees vs Detroit Tigers Over/Under

The Yankees and Tigers have shown scoring potential, averaging close to 8 runs in their recent matchups. However, with the Yankees dealing with key injuries and the Tigers’ inconsistent offense, the total could swing in either direction. How the starting pitchers perform will likely dictate if this game hits the over or under.

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46-30
All
33-44
22-15
Home
21-16
24-15
Away
12-28
44-28
as Fav
21-25
2-2
as Dog
12-19
39-37
ATS
34-43
17-20
ATS Home
17-20
22-17
ATS Away
17-23
35-36
O/U
35-39
19-16
O/U Home
16-19
16-20
O/U Away
19-20
RESULT
LOSE 4-1
DATE
06/21
SPREAD
β€”
O/U
u8.0
RESULT
LOSE 10-2
DATE
06/20
SPREAD
β€”
O/U
o9.0
RESULT
WIN 0-5
DATE
06/19
SPREAD
-1.5
O/U
u8.5
RESULT
LOSE 5-1
DATE
06/18
SPREAD
β€”
O/U
u9.0
RESULT
WIN 5-10
DATE
06/17
SPREAD
β€”
O/U
o8.5
RESULT
WIN 4-1
DATE
05/24
SPREAD
β€”
O/U
u8.5
RESULT
WIN 4-5
DATE
06/21
SPREAD
β€”
O/U
o8.0
RESULT
WIN 1-4
DATE
06/20
SPREAD
-1.5
O/U
u8.5
RESULT
WIN 3-4
DATE
06/19
SPREAD
β€”
O/U
u7.5
RESULT
LOSE 2-4
DATE
06/17
SPREAD
β€”
O/U
u8.5
WHO WON
Yankees logo NYY
RESULT
3-9
DATE
09/11
WHO WON
Tigers logo DET
RESULT
11-1
DATE
09/10
WHO WON
Tigers logo DET
RESULT
12-2
DATE
09/09
WHO WON
Yankees logo NYY
RESULT
4-3
DATE
04/09
WHO WON
Tigers logo DET
RESULT
0-5
DATE
04/08

BOX SCORE: MLB TEAM STATS & PLAYER STATS

0
At Bats
0
0
Runs
0
0
Hits
0
0
Walks
0
0
Strikeouts
0
0.331
On Base Percentage
0.314
0.439
Slugging Percentage
0.393
3.35
Earned Run Average
3.85
0
Earned Runs
0
0
Home Runs
0
0
Walks
0
0
Strikeouts
0
0
Strikeouts Per 9 Innings
0
1.18
Walks Plus Hits Per Inning Pitched
1.27
Batters
AVG
HR
RBI
H
0.276
11
49
76
0.293
22
53
77
0.226
11
31
59
0.232
8
35
52
0.248
17
38
53
0.210
8
23
39
0.289
12
37
52
0.163
4
7
24
0.250
6
20
28
0.258
1
13
23
0.188
0
7
16
0.207
0
3
6
Starting pitcher
W-L
ERA
WHIP
K
Pitchers
W-L
ERA
WHIP
K
8-3
1.71
0.90
109
2-5
4.13
1.13
89
7-2
3.45
1.33
84
4-1
1.73
1.24
38
3-2
3.50
1.25
41
2-1
2.91
1.32
23
4-2
2.20
1.22
41
2-3
3.52
1.34
38
3-0
5.22
1.23
28
3-2
4.35
1.14
15
0-0
4.28
1.17
23
1-1
4.88
1.33
27
0-0
0.00
2.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0

INJURY REPORT

NAME
POS
STATUS
INJURY
NOTES
POS
CF
STATUS
Questionable
INJURY
Knee
Notes
Grisham is dealing with an injury to his left knee and is uncertain to take the field for the Yankees.
full roster and injuries
Batters
AVG
HR
RBI
H
0.290
8
33
81
0.283
6
26
78
0.269
18
55
70
0.208
12
30
53
0.260
4
16
53
0.200
5
26
38
0.180
7
17
29
0.177
2
11
26
0.231
2
10
24
0.146
2
7
13
0.154
1
6
10
0.158
2
5
6
Starting pitcher
W-L
ERA
WHIP
K
3-5
4.09
1.35
67
Pitchers
W-L
ERA
WHIP
K
3-5
4.09
1.35
67
3-5
3.68
1.00
53
1-8
5.35
1.57
78
2-4
2.58
1.01
52
3-3
3.78
1.28
61
2-0
2.02
1.54
22
1-4
3.60
1.37
31
2-0
4.61
1.35
26
4-1
2.84
1.07
18
3-4
5.92
1.40
23
1-3
4.00
1.11
22
0-2
3.18
1.47
20
0-0
0.00
1.50
1
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
full roster