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Milwaukee Brewers vs Cincinnati Reds Predictions

June 22 07:10 PM (Start in 13 Hours)
Great American Ball Park

Brewers vs. Reds Matchup Overview

The Milwaukee Brewers visit the Cincinnati Reds at Great American Ball Park on June 22nd, 2026, for a 7:10 pm showdown. The Brewers hold a record of 45-29, while the Reds are at 36-39. Check out the betting odds, with the Brewers at -175 on the moneyline and the Reds at +150. The Edge AI sports betting tool can help you find the best bets for this matchup. William Contreras leads the Brewers with a .289 batting average and 6 home runs, while Elly De La Cruz is a key player for the Reds, boasting a .280 average and 12 home runs. Garrett Mitchell is questionable for the Brewers due to back tightness, which could impact their lineup. In recent matchups, the Brewers won two out of three games against the Reds, with the last meeting resulting in a Brewers victory. This adds an interesting layer to the game as both teams look to gain momentum.

Matchup Overview

  • Teams: Milwaukee Brewers vs Cincinnati Reds
  • Date: Monday, June 22, 2026
  • Time: 7:10 PM
  • Venue: Great American Ball Park

Current Betting Odds

  • Spread: Brewers — (—) (-1.5 (-102 BetMGM Sportsbook)), Reds — (—) (+1.5 (-118 BetMGM Sportsbook))
  • Total (Over/Under): 9.5 (-107/-114) (Over 9.5 (-108 BetMGM Sportsbook), Under 9.5 (-112 BetMGM Sportsbook))
  • Moneyline Odds: Brewers -175 (-162 (BetMGM Sportsbook)), Reds +150 (+136 (BetMGM Sportsbook))

Edge AI Win Probabilities

After 1,000 simulations, our model gives the Brewers a win probability of 62%, while the Reds have a win probability of 38%

The Brewers and Reds have a long-standing rivalry, with the Brewers historically holding a slight edge in their all-time record. The Brewers typically rely on a strong pitching staff and power hitting, while the Reds often focus on a balanced offensive approach. When these teams clash, home field advantage at Great American Ball Park can be significant, impacting run production and overall game dynamics, making it a matchup worth watching for bettors.

Projected Final Score

Our Edge AI predicts a final score of Brewers 5-4 Reds with a confidence score of 70%. These projections are based on 1,000 simulations and hundreds of data points, ensuring you have the most accurate predictions to inform your betting strategy.

Point Spread
62%
38%
Confidence Level: 72.1%

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Over/Under
62%
38%
Confidence Level: 58.7%

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Moneyline
62%
38%
Confidence Level: 65.4%

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When the Brewers and Reds clash, it’s a classic battle of styles. Milwaukee leans on its pitching depth and power bats, while Cincinnati often counters with a more contact-oriented lineup, especially at Great American Ball Park where the ball tends to carry. Historically, the money line has favored the home team in this matchup, reflecting the Reds’ edge in familiarity and the dimensions of their park, but the Brewers have shown they can steal games on the road with their strong bullpen.

Milwaukee Brewers vs Cincinnati Reds Moneyline

The Brewers, holding a solid 45-29 record, face off against the Reds at Great American Ball Park. With Milwaukee’s current moneyline sitting at -175, they seem favored, but Cincinnati’s home field could play a significant role in this matchup, especially considering the recent history between these teams.

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Milwaukee Brewers vs Cincinnati Reds Run Line

The Milwaukee Brewers, with a strong road record, might have the edge on the run line against the Cincinnati Reds. However, the Reds’ recent home performance could challenge that, especially if their key players step up. Pay attention to the starting pitching matchup, as it could heavily influence which team covers the spread.

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Milwaukee Brewers vs Cincinnati Reds Over/Under

The Brewers and Reds have combined for an average of 9.5 runs in their recent matchups, reflecting their offensive capabilities. With both teams showcasing key hitters like William Contreras and Elly De La Cruz, the potential for scoring is high. However, the effectiveness of the starting pitchers will play a crucial role in determining if they can keep the runs in check.

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46-29
All
37-39
25-15
Home
19-19
21-14
Away
18-20
40-23
as Fav
20-13
6-6
as Dog
17-26
41-34
ATS
40-36
21-19
ATS Home
15-23
20-15
ATS Away
25-13
34-39
O/U
45-30
18-22
O/U Home
23-15
16-17
O/U Away
22-15
RESULT
LOSE 2-8
DATE
04/04
SPREAD
+1.5
O/U
o8.0
RESULT
WIN 9-4
DATE
06/21
SPREAD
O/U
o9.0
RESULT
LOSE 3-4
DATE
06/20
SPREAD
O/U
u7.5
RESULT
LOSE 2-3
DATE
06/19
SPREAD
-1.5
O/U
u7.5
RESULT
LOSE 4-2
DATE
06/18
SPREAD
O/U
u7.5
RESULT
LOSE 8-1
DATE
05/23
SPREAD
O/U
u9.5
RESULT
WIN 4-1
DATE
06/21
SPREAD
O/U
u8.0
RESULT
WIN 10-2
DATE
06/20
SPREAD
O/U
o9.0
RESULT
LOSE 0-5
DATE
06/19
SPREAD
+1.5
O/U
u8.5
RESULT
LOSE 9-1
DATE
06/17
SPREAD
+1.5
O/U
o9.0
WHO WON
Brewers logo MIL
RESULT
2-4
DATE
09/28
WHO WON
Reds logo CIN
RESULT
7-4
DATE
09/27
WHO WON
Reds logo CIN
RESULT
3-1
DATE
09/26
WHO WON
Reds logo CIN
RESULT
2-3
DATE
08/17
WHO WON
Brewers logo MIL
RESULT
6-5
DATE
08/16

BOX SCORE: MLB TEAM STATS & PLAYER STATS

0
At Bats
0
0
Runs
0
0
Hits
0
0
Walks
0
0
Strikeouts
0
0.338
On Base Percentage
0.310
0.394
Slugging Percentage
0.395
3.45
Earned Run Average
4.59
0
Earned Runs
0
0
Home Runs
0
0
Walks
0
0
Strikeouts
0
0
Strikeouts Per 9 Innings
0
1.19
Walks Plus Hits Per Inning Pitched
1.47
Batters
AVG
HR
RBI
H
0.299
7
46
83
0.259
11
47
70
0.270
13
46
61
0.235
3
29
52
0.248
5
34
51
0.205
0
19
38
0.236
3
12
42
0.301
10
30
53
0.269
5
24
47
0.206
1
14
32
0.222
7
21
26
0.352
2
20
38
0.157
1
11
13
0.200
0
0
4
Starting pitcher
W-L
ERA
WHIP
K
Pitchers
W-L
ERA
WHIP
K
8-3
1.45
0.75
138
8-1
2.50
1.06
87
1-4
5.94
1.46
63
4-3
3.30
1.25
51
3-2
3.40
1.18
47
10-1
3.18
1.37
62
0-0
2.03
1.23
32
1-3
3.19
1.03
24
1-3
4.50
1.27
31
4-2
3.62
1.17
29
1-2
4.00
1.07
37
1-0
6.94
1.76
20
2-1
2.74
1.04
30
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0

INJURY REPORT

NAME
POS
STATUS
INJURY
NOTES
POS
CF
STATUS
Questionable
INJURY
Back
Notes
Mitchell is dealing with tightness in his back and is uncertain to take the field for the Brewers.
full roster and injuries
Batters
AVG
HR
RBI
H
0.252
14
53
72
0.240
12
31
62
0.204
8
25
50
0.280
12
37
65
0.211
6
22
39
0.254
13
35
45
0.257
9
25
43
0.179
2
8
28
0.289
2
5
37
0.142
2
5
17
0.262
3
13
27
0.188
3
6
18
0.231
0
4
6
Starting pitcher
W-L
ERA
WHIP
K
3-6
5.32
1.61
52
Pitchers
W-L
ERA
WHIP
K
9-1
2.00
1.05
102
5-4
3.83
1.42
64
3-6
5.32
1.61
52
0-7
6.96
1.66
39
2-2
6.12
1.59
32
2-3
3.00
1.44
31
1-5
3.19
1.26
34
1-3
5.10
1.40
28
1-0
5.53
1.77
28
1-1
3.33
1.22
32
2-1
3.27
1.23
20
1-0
2.75
0.97
17
0-0
5.40
1.92
13
0-0
0.00
0.00
1
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
0-0
0.00
0.00
0
full roster