Giants vs. 49ers Best Over/Under 9/21/23
New York Giants vs. San Francisco 49ers Game Pick
The New York Giants take on the San Francisco 49ers at Levi's Stadium on Thursday, September 21st, at 8:15 PM EDT
New York Giants vs. San Francisco 49ers Odds
Moneyline: Giants +400 (FanDuel), 49ers -450 (PointsBet)
Point Spread: Giants +10.5 (-110 FanDuel), 49ers -10.0 (-109 BetRivers)
Total: Over 44.5 (-110 FanDuel), Under 45.0 (-109 BetRivers)
Betting Trends
ATS: Giants: 1-1 49ers: 2-0
Over/Under: Giants: 1-1 49ers: 2-0
Matchup Preview
The New York Giants have struggled on offense and will be without Saquon Barkley. On the other side, the 49ers will look to quarterback Brock Purdy to lead their offense. With both teams dealing with injuries, it will be a challenging game in terms of scoring.
Total Pick: Under
Lines.com 9/17 6:00 PM
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