Cardinals vs. Bills Best Point Spread 9/8/24
Arizona Cardinals vs. Buffalo Bills Game Pick
The Arizona Cardinals take on the Buffalo Bills at Highmark Stadium on Sunday, September 8th, at 1:00 PM EDT
Arizona Cardinals vs. Buffalo Bills Odds
Moneyline: Cardinals +225 (BetMGM), Bills -260 (FanDuel)
Point Spread: Cardinals +6.0 (-110 Caesars Casino), Bills -5.5 (-118 FanDuel)
Total: Over 48.0 (-109 BetRivers), Under 48.5 (-105 FanDuel)
Betting Trends
ATS: Cardinals: 0-2 Bills: 2-0
Over/Under: Cardinals: 1-1 Bills: 0-2
Matchup Preview
Josh Allen and the Buffalo Bills will be facing off against the Arizona Cardinals at Highmark Stadium. Allen has the arm strength and toughness to make big plays under pressure, and he also has the athletic ability to make big plays with his legs. He has a new crew of receivers with Curtis Samuel leading the way, and he will also depend on James Cook to provide a top-tier running attack.
The Cardinals have a very difficult assignment in their opener, because they will face a nasty opponent in front of a hostile crowd. Kyler Murray is capable of spectacular plays, but he will also make his share of mistakes. Rookie wideout Marvin Harrison Jr. is a potential rookie of the year.
Spread pick: Bills
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