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Over 48.5
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Cardinals vs. Bills Best Over/Under 9/8/24

Cardinals vs. Bills Best Over/Under 9/8/24

FINAL
28-34
CBS
Highmark Stadium
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Arizona Cardinals vs. Buffalo Bills Game Pick

The Arizona Cardinals take on the Buffalo Bills at Highmark Stadium on Sunday, September 8th, at 1:00 PM EDT

Arizona Cardinals vs. Buffalo Bills Odds

Moneyline: Cardinals +225 (BetMGM), Bills -260 (FanDuel)

Point Spread: Cardinals +6.0 (-110 Caesars Casino), Bills -5.5 (-118 FanDuel)

Total: Over 48.0 (-109 BetRivers), Under 48.5 (-105 FanDuel)

Betting Trends

ATS: Cardinals: 0-2 Bills: 1-1

Over/Under: Cardinals: 1-1 Bills: 1-1

Matchup Preview

Josh Allen will attempt to get the Bills off to an excellent start at home against their NFC visitors. The Bills have displayed big-play ability throughout Allen's run in upstate New York, but the quarterback has also shown off a tendency to make risky plays and turn the ball over. The Cardinals are hoping that rookie wideout Marvin Harrison Jr. is the key to getting quarterback Kyler Murray untracked.

Our pick: over

Lines.com 9/1 10:00 AM
NFL Computer Pick
Over 48.5
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